Therapeutic Platform for the Treatment of Lung Disorders

Pneuma’s therapeutic platform has been designed to treat a range of lung disorders, including non-small cell lung cancer and COPD. The platform is designed to have the following unique features:

Low Shear Delivery

Our technology can deliver fragile molecules, such as immunotherapy biologics, with little shearing or denaturing.

Digital Breath Actuation

Our device has been designed to sense when the user begins to inhale and automatically eject the prescribed dose of drug without timing problems and without propellants.

High Respirable Fraction

Our technology produces aerosols with very high respirable fractions of up to 90%, allowing for high concentrations of a drug to be delivered directly to the lungs.

Ease-Of-Use

The device does not require shaking, priming, or marked physical pressure to operate, making it easy for children and seniors to use.

The device has been designed with the ability to deliver prompts, via voice or tones, which we believe may help patients use the device correctly.

Dose Verification

Sensors in the device will be able to verify that the drug or medicine has indeed been inhaled.

Improved Patient Compliance

Data will be wirelessly captured and released via Bluetooth™ to the cloud for use by patients and physicians. The rapid feedback to physicians is expected to greatly increase the degree to which patients comply with their prescribed treatments (a key source of treatment failure).

High Dose Confidence Mode

The device designed to include a High Dose Confidence (HDC) mode. In HDC mode, the device will calculate the dose left to be inhaled if the patient does not complete their inhalation over a fixed time. In the HDC mode, the device measures the remaining dose and issues the voice command “Please inhale again to complete your dose” and continues to do so for up to three times if the patient does not fully complete their dose. If a complete dose cannot be given, that information is sent to the cloud via a smartphone app where the doctor can see the missed doses along with other compliance data.